South West Sydney is a dynamic centre for clinical trials.
At any given time we have over 300 trials open in a broad range of specialty areas. At the Ingham Institute and in South West Sydney Local Health District, through the work of our dedicated clinical trials units we have improved health outcomes for our community.
Clinical trials can evaluate medicines, procedures, medical devices, and other health treatments. They are divided into different stages, called phases. The earlier phase trials look at whether an intervention is safe and effective, whilst later phase trials aim to test whether new treatments are better than existing treatments.
Within South West Sydney Local Health district we have over 20 clinical trials Groups that cover more than 15 different specialty areas. This footprint that covers Liverpool, Campbelltown, Bankstown, Bowral and Fairfield Hospitals. The largest groups work directly from the Ingham Institute with close ties to with University of New South Wales, and the Western Sydney University.
Since early 2015 the Sout West Sydney Local Health District together with the support of the Ingham Institute established a clinical trials support unit (CTSU). This Unit provides supports our dynamic research culture and provides a framework for clinical trial governance that includes onsite Good Clinical Practice training, established Standard Operating Procedures and finance support services. We have achieved this through working closely with our supporting departments such as the Research and Ethics Office, Pathology and Pharmacy departments. We also place high emphasis in working with Sponsors and Researchers to drive efficient start up process and achieving successful recruitment targets.
In 2015, Ingham Institute’s Director of Palliative Care research and the SWSLHD Director of Clinical Trials Professor Meera Agar, received funding for Australia’s first medical cannabis trial for terminally ill cancer patients.
The trial is studying whether medical cannabis improves the quality of life for adults with terminal cancer. It will ascertain whether medicinal cannabis improves appetite and appetiterelated symptoms in people receiving palliative care for advanced cancer. It will also evaluate its potential to help with other symptoms including fatigue, low mood, weight loss, nausea, insomnia and pain.
The medical cannabis clinical trial represents a huge leap forward in the evaluation of treatment options available to terminally ill cancer patients in Australia. Other Ingham Institute researchers are working on clinical trials to find new treatments for conditions including multiple sclerosis and blood diseases, such as leukaemia and lymphoma.
If you think that yourself or someone you care for might benefit from participating in a clinical
trial please visit www.australianclinicaltrials.gov.au and speak with your doctor.
Focuses on inflammatory bowel disease
Focuses on asthma, chronic obstructive pulmonary disease, lung disease, sleep disorders, pulmonary hypertension (high blood pressure affecting arteries in the heart and lungs) and tuberculosis
Focuses on inflammatory bowel disease (including Crohn’s Disease and ulcerative colitis), hepatitis B and C, and liver cancer
Focuses on malignant and non-malignant blood diseases
Focuses on intensive care, sepsis and septic shock (a life threatening complication of an infection), traumatic brain injury, nutrition, organ and tissue donation, and cardiac arrest
Focuses on diabetes, anaemia, kidney transplants, high blood pressure, inflammation of the kidney (caused by lupus), diabetic nerve damage, chronic kidney disease and overactive parathyroid glands
Focuses on cancers of the breast, lung, gastro-intestinal system and pancreas
A/Professor Suzanne Hodgkinson Neurologist has a strong interest in Multiple Sclerosis. There are now several Neurologists in the local area who have a strong MS focus. Their expertise, commitment and ongoing contributions now permit the Multiple Sclerosis clinic to offer a Multidisciplinary Services that includes Medical, Neuropsychological, and Nursing support.
The aim of the service is to provide support to clients with acute and chronic illness, in attempt to delay the onset of symptomatic disease and hospital admission.
The Multiple Sclerosis clinic participates in several International clinical trials thus providing access to the most innovative therapeutic interventions being explored. The specialty focused clinic strives to promote and maintain clinical excellence and ensure new discoveries are rapidly and effectively applied to patients in the South Western Sydney Health Network.
Focuses on cancers of the breast, prostate, colon, brain, liver, lung, kidney, pancreas, rectum and female reproductive system
Focuses on improving symptom control for people living with anorexia, cancer pain, delirium, breathing difficulties, constipation, nausea and sleep disturbance. The group also focuses on advanced dementia
Focuses on outcomes after orthopaedic trauma surgery, joint reconstruction or replacements, and hip fracture surgery. The group also focuses on physiotherapy rehabilitation after total knee replacement and clinical practice variations.
The Immunology and Allergy Unit at Campbelltown Hospital offers a comprehensive,multidisciplinary service to children and adults. We have a large population of patients with immunodeficiency and we have developed expertise and protocols for home-based treatment. We have expertise in autoimmune disease diagnosis and management, employing newer therapies. Our allergy service is extensive, catering to the needs of those with respiratory allergy, particularly severe asthma; dermatological conditions such as atopic dermatitis and urticaria; drug allergy, including a drug testing service for perioperative anaphylaxis and antibiotic allergy; all aspects of food allergy, with a food challenge clinic in the paediatric service. We conduct a specialised angioedema and urticaria clinic catering for those requiring immunomodulating therapy and management of rare diseases.
Our Unit has a long history of conducting clinical trials and continues to participate in a number of international clinical trials investigating new monoclonal antibody therapy in severe asthma in adults and most recently, in children. We have conducted several studies using new treatments in the rare inherited disorder Hereditary Angioedema and in clinical trials with immunodeficiency treatment. We participate in a multicentre paediatric study investigating peanut allergy in children and have conducted original research into behavioural aspects of food allergy. Drug allergy is another area of active research for our unit. Finally, we have conducted aerobiological surveys of the South West Sydney region for the last 10 years offering daily pollen count reporting via a free app during the Spring. We are major participants in an NHMRC grant for setting up pollen monitoring throughout Australia.
The Radiation Oncology Clinical Trials team has a strong focus on investigator initiated and collaborative group clinical trials.
Please refer to http://www.anzctr.org.au for more information on clinical trials that are being run from the institute.
If you think that you or someone you care for might benefit from participating in a clinical trial please speak with your doctor.
You can also find out more about clinical trials by visiting Australian Clinical Trials.
To learn more about sponsoring a Clinical Trial at the Ingham Institute, contact us today.