Lois Holloway leads the medical physics group at the Ingham Institute and Liverpool and Macarthur Cancer Therapy centres. She has a long interest in mathematical modelling for radiotherapy and is excited by ongoing developments and opportunities in both imaging and machine learning in this area. She leads the OzCAT (Computer Assisted Theragnostics) working to link distributed datasets to develop prognostic models for radiotherapy, particularly for situations where randomised clinical trial evidence is limited.