Gastro-Intestinal Viral Oncology Group

The Gastro-Intestinal Viral Oncology Group focuses on infectious causes of Gastro-Intestinal Cancer with a special emphasis on Barrett's Oesophagus, a precancerous condition of the oesophagus.

This was the first group in the world to hypothesise and publish that high risk Human Papilloma Virus (HPV) may be associated with precancerous and cancerous lesions of the oesophagus based on similarities in immunology and genetics with cervical tumours. Initial results of their research support this theory, with the group’s work to potentially lead to a vaccination against certain types of Oesophageal Cancer.

In addition to this, it was the first in the world to isolate a gene associated with Barrett's Oesophagus and to demonstrate that the bacterium Helicobacter pylori reduced the length of the precancerous segment in the oesophagus by almost 50 per cent.

The group is supported by the Mark Grundy Oesophagael Cancer Awareness Group Inc (OCAGI) and has collaborations with the Westmead Millennium Institute for Medical Research and the School of Human Life Sciences, University of Tasmania, Launceston

Group Leader:
Professor Shan Rajendra
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